Baig, AnwarGhole, Sahar Junaid (22PH64)Sayed, Tazeen Zahra Zaheer Asad (22PH65)Shetty, Sharad Raveendra (22PH96)Sunera, Salim Ali Mohd. Kausar (22PH101)Tripathi, Tanu Ved Prakash (22PH103)2026-06-302026-06-302026-05http://aiktc.ndl.gov.in/handle/123456789/4530In an era where obesity and lifestyle disorders like diabetes and hypertension are surging due to sedentary habits, processed foods, and stress especially in urban India this study develops and evaluates a multigrain, protein-enriched meal replacement porridge as a practical therapy for obesity management. Using locally sourced superfoods like bajra (pearl millet), ragi (finger millet), pea protein, gorakhmundi, cocoa powder, date powder, stevia, almond powder, and cardamom, the formulation promotes satiety via low glycaemic index fibres, supports lean mass preservation with branched-chain amino acids, enhances fat metabolism through anti-inflammatory bio actives, and boosts palatability for better adherence .all while being affordable and gut-friendly. Comprehensive in-silico molecular docking revealed strong binding affinities of key ingredients to obesity-related targets like adipocyte receptors; in-vitro tests confirmed nutritional superiority (high protein/fibre, low carbs), pharmaceutical stability (solubility, shelf-life), and microbial safety (no pathogens), positioning this as a sustainable, evidence-backed alternative to sugary commercial meal replacements for long-term weight control and metabolic health.en-USDevelopment and evaluation of multigrain protein-enriched herbal meal replacement therapy for obesity management: an in-silico and in-vitro studyProject Report