Browsing by Author "Gaikwad, Madhuri"

Now showing 1 - 8 of 8
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    Aerosol
    (AIKTC, 2018) Gaikwad, Madhuri
    Subject: Pharmaceutics-II; Class: T.Y. B. Pharm. (Sem.- I)
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    Anti-acne formulation
    (AIKTC, 2020-05) Gaikwad, Madhuri; Khan, Maseera Banu Fazlur Rehman (16PH23); Quadri, Heena Kausar Mohammed Umer (16PH36); Khan, Uzma Khatoon Abdul Muttlib (16PH28); Khatib, Rahil Abdul Rauf (16PH29)
    Acne often debuts during changes in hormonal level in pre-teens and also caused by the bacteria P. Acnes. The isolation of the herbal active principle and the determination of their structure, in order that they are synthesized or simply extracted more efficiently. Allopathy means modem scientific medicine which leads to adverse drug reaction as allopathic drugs are in chemical form. As Dr. Manoj Nesari joint adviser department of Ayush states that "there is rising trend towards Ayurveda". And the demand for herbal products world-wide has increased at an annual rate of 8%. Manjistha commonly knows as Rubia Cordifolia works on P. Acnes and its anthraquinone rich constitutent also contains anti-inflammatory, anti­ bacterial and anti-oxidant propety. The cream, gel and ointment formulations are prepared using alcoholic, water and alcoholic extract respectively. The formulations are characterized and evaluated on the basis of its organoleptic properties, pH values, viscosity measurement, spreadability, stress testing and determination of invitro anti-acne activity. The organoleptic properties shows that the formulations are cosmetically appealing. Cream was found to be oil soluble and pH values of formulations was found to be stable after 2 weeks. Viscosity was found to be 1500-2000 cp. Spreadability of formulations was found to be in range of 10-25 mm. Stress testing shows that the formulation has good shelf-life. And the antimicrobial activity is compared between cream, gel and ointment. Keywords Acne, P.acnes, herbal products, Manjistha, anti-inflammatory property, anti-bacterial property, anti-oxidant, property, gel, cream, ointment, anti-acne activity, anti-microbial activity.
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    Drug and magic remedies act
    (AIKTC, 2018) Gaikwad, Madhuri
    Subject: Pharmaceutical Jurisprudence; Class: Final.Y. B. Pharm. (Sem.- VII)
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    Excise duty
    (AIKTC, 2018) Gaikwad, Madhuri
    Subject: Pharmaceutical Jurisprudence; Class: Final.Y. B. Pharm. (Sem.- VII)
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    Formulation and evaluation of transfersomal cream of Acriflavin
    (International Research Journal Of Pharmacy, 2016-09) Gaikwad, Madhuri
    A burn can be major medical problems or life threatening emergencies admitted to any hospital. Conventional topical burn formulations are required to be applied 3 to 4 times a day and previous application is needed to be removed prior to application of each new dose which is very painful to burn patients. In this research an attempt was made to increase the patient compliance by reducing the dosing frequency through sustained released vesicular drug delivery system like transfersomes. Transfersomes were formulated using by thin film hydration method and evaluated for entrapment efficiency, photo microscopy, scanning electron microscopy, vesicle size, poly dispersity and zeta potential. optimized transfersomal batch was incorporated in cream base and evaluated for pH, spread ability, viscosity, grud contyent and in-vitro diffusion. Transfersomes prepared by using 1:3 ratio of Sodium cholate with cholesterol and 200 mg drug showed highest entrapment(91.65%) and sustained release(65.18% in was 24 hrs.)was obtained with transfersomal cream in comparison with conventional formulation(97.54%) in 8 hrs.
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    Nanofiber reinforced hydrogel patch for cosmetic scar management
    (AIKTC, 2026-06) Gaikwad, Madhuri; Saloni, Nandkumar Ghanekar (22PH17); Kunal Ramchandra Gupta (22PH18); Sherebano, Moiz Najmee (22PH54); Jasmine A Razzak Parkar (22PH57); Pathan, Almas Mohin (22PH58)
    This study displays the development and evaluation of a biomimetic nanofiber-reinforced hydrogel patch tailored for the cosmetic management of hypertrophic scars and keloids. The composite patch mimics the skin's natural extracellular matrix using an electrospun polyvinyl alcohol (PVA) nanofiber layer and a sodium alginate-gelatinee hydrogel base. It co-delivers tranexamic acid within the hydrogel to target hyperpigmentation and copper tripeptide-1 embedded in the nanofibers to promote organized collagen remodelling. Physicochemical evaluations revealed a skin-compatible pH of 5.5, high swelling capacity for optimal moisture retention, and an 83.55% gel fraction ensuring structural durability. Scanning electron microscopy confirmed a uniform, bead-free nanofiber network, while FTIR analysis validated the chemical stability and successful loading of the active ingredients. In vitro studies demonstrated a controlled, sustained biphasic drug release profile and verified antimicrobial efficacy against Staphylococcus aureus. The dual-drug composite system successfully provides a safe, structurally robust, and biomimetic platform for accelerated tissue regeneration and scar reduction. Keywords Nanofiber-reinforced hydrogel, Scar management, Electrospinning, Tranexamic acid, Copper tripeptide-1, Biomimetic patch, Sustained drug delivery.
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    Suppository
    (AIKTC, 2018) Gaikwad, Madhuri
    Subject: Pharmaceutics-II; Class: T.Y. B. Pharm. (Sem.- I)
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    Suspension
    (AIKTC, 2018) Gaikwad, Madhuri
    Subject: Pharmaceutics-II; Class: T.Y. B. Pharm. (Sem.- I)