Browsing by Author "Shaikh, Junaid Nizam (22PH79)"

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    Formulation and pharmacological evaluation of herbal hair protective hydrogel
    (AIKTC, 2026-07) Shaikh, Abusufyan Sirajuddin; Shaikh, Eram Mohd Iqbal (22PH77); Shaikh, Junaid Nizam (22PH79); Shaikh, Maseera Kalim (22PH81); Shaikh Meraz Raza Imtiaz Raza (22PH82)
    Hair greying and hair fall are common cosmetic concerns associated with oxidative stress, reduced melanogenesis, follicular damage, and environmental exposure. The present study focuses on the formulation and pharmacological evaluation of a herbal hair protective hydrogel incorporating a synergistic blend of natural bioactive ingredients and therapeutic agents for comprehensive hair care management. The formulation was developed using herbal extracts of Nigella sativa (black seed), Eclipta alba (bhringraj), Phyllanthus emblica (amla), Camellia sinensis (green tea), and Salvia rosmarinus (rosemary), along with L-Tyrosine and Copper(II) acetate as key active pharmaceutical ingredients to support melanin synthesis and promote hair follicle health. The hydrogel was formulated using an appropriate gelling system to ensure optimal physicochemical stability, ease of application, and enhanced scalp adherence. The prepared formulation was evaluated for various parameters including appearance, pH, viscosity, spreadability, homogeneity, stability, and compatibility. Pharmacological evaluation was performed to assess its potential antioxidant and hair protective activity. The combination of herbal bioactives and targeted active ingredients demonstrated promising potential for reducing oxidative damage, supporting natural hair pigmentation, strengthening hair follicles, and improving overall scalp health. The developed herbal hydrogel offers a safe, effective, and patient-friendly topical approach for hair protection and management, presenting a promising alternative to conventional synthetic hair care formulations. Keywords:- Herbal Hydrogel, Hair Greying, Hair Fall, Antioxidant Activity, Melanogenesis, Hair Follicle Protection, Polyherbal Formulation