Evaluation of curculigo orchioides mucilage as suspending agent
No Thumbnail Available
Date
2011-04
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of PharmTech Research
Abstract
Plant products served as an alternative to synthetic products because of local accessibility, eco friendly
nature and lower prices compared to imported synthetic products. The present study was undertaken to evaluate the
mucilage obtained from the roots of Curculigo orchioides Gaertn. as a suspending agent. Characterization studies like
solubility, swelling index, loss on drying, ash value, pH, viscosity along with microbial load and acute toxicity studies
were carried out on the mucilage. Aluminium hydroxide gel suspension was prepared using different concentration of
Curculigo orchioides mucilage and its properties were compared with standard suspending agents like sodium
carboxymethylcellulose and Acacia. The evaluation parameters included the sedimentation profile, redispersability,
rheology and particle size analysis. The results suggested that the mucilage was found to be a superior suspending agent
than acacia indicating that it may be a good source as pharmaceutical adjuvant.
Description
Keywords
Staff Publication - SoP